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3), supporting our previous metabolic assays showing that PPP activity mainly supports fatty acid oxidation, the TCA cycle, and nucleotide synthesis

Muscle contractile function was markedly restored, accompanied by significantly elevated proliferation activity and number of muscle stem cells, as well as upregulated expression of myogenic differentiationrelated genes

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It inhibits gluconeogenesis and stimulates glycolysis by modulating the intracellular concentration of fructose 2,6-bisphosphate in the liver